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Heartburn Medication Kidney Damage Side Effects May Go Unnoticed Researchers say in a new study that prolonged use of proton pump inhibitors (PPIs), or heartburn medications, are associated with an increased risk of kidney damage. According to a CBS news report, the new study, which was published in the journal Kidney International, looked at adults who use heartburn medications sold under brand names such as Prevacid, Nexium and Prilosec, as well as users of H2 blockers, such as Zantac or Pepcid. These findings could affect roughly fifteen million Americans who use these prescription drugs for heartburn and acid reflux. Thousands of injured patients have filed heartburn medication lawsuits across the country. What Did Researchers Find? Researchers at Washington University School of Medicine in St. Louis and the Veterans Affairs St. Louis Health Care System analyzed data from VA databases on 125,596 new users of PPIs and 18,436 new users of H2 blockers. They found that H2 blockers are much less likely to cause kidney problems than PPIs. Over five years of follow up, researchers found that more than 80 percent of PPI users did not develop acute kidney problems. However, more than half of the cases of chronic kidney damage and end-stage renal disease associated with PPI use occurred in people without acute kidney problems. Researchers said doctors should pay careful attention to kidney function in their patients who use PPIs even when there are no signs of problems. Doctors should also evaluate whether PPI use is medically necessary because these drugs carry significant risks, including a deterioration of kidney function. What are the Dangers of Heartburn Medication? Studies show that heartburn medications cause acute interstitial nephritis, which involves irritation and inflammation of the kidneys, which could lead to chronic and long-term injury if the drug is not discontinued. Patients could also suffer acute kidney injury, which includes the sudden loss of kidney